Mark Cuban Says AI Agents Can Be Used to Fight AI-Driven Hacks

Investor compares automated attackers with a swarm of pests

Entrepreneur and investor Mark Cuban said companies should be able to use artificial intelligence to protect themselves from AI-driven hacking agents, telling Reuters he was not pessimistic about the technology.

Speaking at Reuters Total Health in Nashville, Cuban compared automated attacks to cockroaches that repeatedly find ways into a house. He said malicious actors could use AI in a brute-force way, but defenders could also apply comparable computing power to identify and stop threats. His comments were an opinion about how companies might respond, not a report of a new security product.

Cuban also discussed Cost Plus Drugs, the online pharmacy he founded in 2022. The company uses a pricing model based on its cost for a drug plus 15% and joined TrumpRx.gov in May, according to Reuters. It began making sterile injectable drugs typically used in hospitals in 2025 at its own compounding manufacturing facility.

Portable manufacturing remains subject to approval

Cuban said the company had built smaller, tractor-trailer-sized manufacturing facilities, or “pods,” that could operate separately or together to make generics, rare-disease treatments and other medicines. He said the pods could eventually become Cost Plus Drugs’ largest business and allow production closer to where medicines are needed, including during a disaster.

He said the company was still speaking with the US Food and Drug Administration to obtain approval for the pods and did not describe the unresolved issues. Reuters did not report that the facilities had received FDA approval. Cuban also said the US government should count out-of-pocket payments toward patients’ deductibles and make taxpayer-funded health contracts public without redactions.

Sources

https://www.reuters.com/business/healthcare-pharmaceuticals/mark-cuban-says-ai-hack-agents-are-like-cockroaches-can-be-controlled-2026-10-23/